Traditional Aseptic Fillers, Compact Filling Line
Our Compact Filling Line processes vials, cartridges, syringes or ampoules. The system includes a Rotary Washer, Depyrogenation Tunnel, Filler-Stoppering-Capper System and Isolator or RABS. Further, our compact line features the smallest foot print in the world and is suitable for clinical manufacturing, laboratory plus R and D applications. With a small foot print (less than 15 feet long), the only thing big about this system is the energy saving features it offers. Several models and options are available for a customized solution to your specific application.
Included in our Complete Compact Filling Lines is Steriline’s RA Series Rotary Washers. Our RA Series Washers use typical European style gripper mechanisms to handle the glassware, ensuring thorough and consistent washing. Moreover, the washer is equipped with needles which are lifted to penetrate the glassware and then spray the appropriate washing and drying fluids. After washing, the glassware is up-righted and directly discharged onto the Depyrogenation Tunnel.
The vials pass through the inlet chamber then enter the hot chamber where the depyrogenation process takes place. The glassware then enters the cooling chamber to cool down to a suitable temperature before discharge onto the rotary in-feed table of the filler. The filler can be equipped for any type of pump with several purging options. The filler and capper are separated to ensure process control over the separate functions. After filling, the vials can be immediately capped or removed for Lyophilization. Many options are available, including the ability to capper vials after lyophilization, 21 CFR Part 11 compliance, sterilizable cooling zone, various enclosure types over the filler, etc. An exterior vial washer is also available to ensure the safety of your workers in downstream packaging areas. The depyrogenation tunnel has the added advantage of the air being recycled in each of the three chambers due to the absence of intake and exhaust ducts in the hot zone. The pressure differential between the cooling chamber and the inlet chamber allows for approximately 100 air changes per hour in each chamber. The highly accurate automatic control of air speed in the chambers and of the pressure control inside the tunnel has always been one of the greatest advantages of Steriline’s depyrogenation tunnels. Combine the compact line with other processing options and modular cleanrooms.