AWS Bio-Pharma Technologies, LLC    

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AWS Bio-Pharma

[New!]Consulting Services

Owner-Engineer Consulting

 

By Product:

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Aseptic Processing

  • Washing

    • Rotary Washers

    • In-Line Washers

    • Exterior Vial Washers

    • Equipment/Parts Washers

  • Sterilization & Depyrogenation

    • Sterilization & Depyrogenation Tunnels

    • Depyrogenation Ovens

    • Autoclaves

  • Filling

    • VFM Monoblock

    • Precision, Long-life Peristaltic System

  • Stopper Processing

    • Stopper Washers

    • Stopper Washer/Sterilizing

  • Capping

    • Aseptic Capping

    • Rotary Capper

  • Isolation Devices

    • R.A.B.S.

    • Isolators

    • Laminar Flow Units

  • Transfer & Other Devices

    • Accumulation Tables

    • Transfer Disks

    • Sanitary Conveyors

    • Tunnel Loaders

    • Tray (Un)Loaders

    • Syringe Loaders

    • Automatic Lyo Loader/Unloader

    • Trays

    • Racks & Carts

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Non-Aseptic Processing

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Packaging Equipment

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Facility & Support Systems

By Company:

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Aseptic Processing

  • Steriline

    • Washers

    • Depyrogenation

    • Fillers / Cappers

    • Isolation Devices

    • Exterior Washers

  • PennTech

    • Washers

    • Tray loaders

    • Conveyors

    • Lyophilizers

    • Lyo-loading systems

  • BEAM

    • MajiCap Capping

  • ICOS

    • Ovens

    • Autoclaves

    • Stopper/Washer Processing

    • Glassware Washers

  • Hurst

    • Label Removal Systems

    • Trays, Racks, & Carts

    • Tray Loaders & Unloaders

  • Dabrico

    • Semi-Automatic Parenteral Inspection

  • Colanar

    • Precision, Long-Life Peristaltic Filing Systems

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Non-Aseptic Processing & Packaging

  • NICOMAC

    • Modular Clean Rooms & Accessories

    • Tablet Presses

    • Tablet Coaters

    • Powder Processing

  • Hurst

    • Label Removal Systems

    • Trays, Racks, & Carts

    • Tray Loaders & Unloaders

  • Capmatic

    • Unscramblers

    • Fillers

    • Cappers

    • Labelers

    • Banders

    • Cotton & Desiccant Inserters

    • Cartoners

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Facility & Support Systems

  • A&B Process Systems

    • Formulation Tanks, Reactors, Other Vessels

    • WFI Distribution, Tanks

    • Hi-Purity process piping

  • Cal-Chem

    • Passivation of Stainless Steel

  • MicroWest

    • Computerized Maintenance Management Systems

 

AWS represents the highest quality, new biotech and pharmaceutical manufacturing equipment

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 



About Nicomac

NICOMAC Company Mission: Our Goal is High Quality and the Highest Technology for your success

NICOMAC was founded in 1977. Our success all over the world is due to our Company Philosophy focused on a constant innovation and care of customer.  We aim to become the partner of choice by providing solutions based on advanced and unique technologies that give to our customer a competitive advantage.

All NICOMAC projects are based on detailed drawings, controlled and validated design, care of details, respect of the production and installation time schedule, fast and reactive communication. A young, dynamic, flexible organization, who pay high attention of customer's requirements, skilled and experienced personnel , proactive and communicative management will take you to success of your valuable projects.  Nicomac has 4 lines of products:

  • NCS Nicomatic Coating System combines a unique design with unmatched coating equipment performance, high technology and versatility for today's ever-evolving pharmaceutical and confectionery processing field.
  • HI HIPHARMA Clean Room line is Nicomac's answer to the high quality standard required by the Pharmaceutical industry. Our clean rooms system combine quality and innovation at a competitive price. Standard and custom walls, doors, false ceilings, and accessories: the most advanced systems in the marketplace.
  • NGL Granulation line - A complete line of granulation machinery for a turn-key supply: Dispensing Room, Granulation , Handling, Mixing.
  • Download PDF - Nicomac General Presentation and Overview

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Table Top, Lab Scale Tablet Press

    Nicomac's MINITAB Series of Single Rotary Tablet Presses is an idea press for R&D operations, designed with Flexibility, Reliability, and Ease of Scale-Up in mind.  With a max output of 27,000 tablets/hr, and available tooling for D, B, or BB tablets, the MINITAB Tablet Press is perfect for your R&D and lab operations

  • MINITAB Tabletop Rotary Tablet Press made by NICOMAC
  • Can be integrated with APPS
  • D, B, BB Tooling for up to 27,000 tablets/hr
  • cGMP and CE compliant
  • Max compressive force of 10tons
  • Machine dimensions - 0.46m x 0.62m x 1.1m (+table)
  • Download PDF - MINITAB Brochure

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Single Rotary Tablet Press

    Nicomac's NIK SMART Series of Single Rotary Tablet Presses are one of the most modern, compact, and reliable rotary presses on the market.  With a max output of 118,000 tablets/hr, and available tooling for D, B, or BB tablets, the SMART Tablet Press is perfect for your low to mid speed applications

  • Can be integrated with APPS
  • cGMP and CE compliant
  • Max compressive force of 10tons
  • Machine dimensions - 1m x 1m x 1.8m
  • Precompression for difficult/fluffy/fine granules
  • HOS: Hydraulic Overload System to protect turret/dies/punches and avoid possible damage
  • Interlocking on upper and lower guards and audio visual alarm available for maximum safety
  • Download PDF - All Rotary Tablet Presses

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Double Rotary Tablet Presses

    Nicomac's NIK CLASSIC Series of Double Rotary Tablet Presses are made for production efficiency and the highest reliability on the market.  It  be configured for double output or double layer execution.  With a max output of 270,000 tablets/hr, and available tooling for D, B, or BB tablets, the CLASSIC Tablet Press is perfect for your mid to mid/hi speed applications

  • Optimized for stability and maximum operating reliability
  • cGMP and CE compliant
  • PLC Control and HMI w/alphanumeric display
  • Compression Spring Counterbalance System
  • HOS, Pre Compression and 3-way Discharge is not available on this model
  • Machine dimensions - 1.1m x 1.1m x 1.8m
  • Interchangeable Gravity Feeder or Force Feeder
  • Interlocking on upper and lower guards and audio visual alarm available for maximum safety
  • Download PDF - All Rotary Tablet Presses

    Nicomac's NIK SPECIAL Series of Double Rotary Tablet Presses have an ultra-modern design using unique sliding pressure rolls.  With a max output of 583,000 tablets/hr, and available tooling for D, B, BB or BBsp tablets, the NIK SPECIAL Tablet Press is perfect for your mid to hi speed applications

  • Unique sliding pressure rolls
  • Optimized Stability and dust tight seals
  • No cross contamination
  • D, B, BB and BBsp Tooling for up to 583,000 tablets/hr
  • cGMP and CE compliant
  • PLC Control and 10.4" Touch screen HMI
  • Machine dimensions - 1.25m x 1.45m x 1.95m
  • Download PDF - All Rotary Tablet Presses

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Triple Rotary Tablet Press

    Nicomac's NIK Triple Series of Triple Rotary Tablet Presses are made for production efficiency and the highest reliability on the market.  It  be configured for triple output or triple layer execution.  With a max output of 658,000 tablets/hr, and available tooling for D, or B tablets, the TRIPLE Tablet Press is perfect for your mid to hi speed applications

  • Unique sliding pressure rolls
  • Compression zone is totally isolated
  • D or B Tooling for up to 658,000 tablets/hr
  • cGMP and CE compliant
  • PLC Control and HMI w/alphanumeric display
  • Machine dimensions - 1.25m x 1.45m x 1.95m
  • Download PDF - All Rotary Tablet Presses

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Conventional Coating Pans

    The Nicomac Coating System (NCS) combines a unique design with unmatched coating performance and versatility for today's ever-evolving processing field. Our system has achieved worldwide success in both the Pharmaceutical and Confectionery industries. The following are just a few of the significant features that set us apart from the competition:

  • Versatility: capable of aqueous & organic film or sugar coating of tablets, pellets

  • Capacity: ranges from lab scale (10L) up to manufacturing production (2,300L)

  • Special drums and Unique drying system allows for same high efficiency when working with 15-20% of the drum capacity

  • Shark Fin Baffles: Patented "3D Shark Fin Baffles" combine higher mixing efficiency with gentler product handling to result in improved coating uniformity, thanks to the uniform distribution of spraying solution, thus reducing overall process time

  • Download PDF here for complete list of Nicomac's Coating System Advantages!

  • Download PDF of Nicomac Coating Line Card



Tablet Processing Accessories

    3-Way Discharge - efficient 3 way discharge with pneumatic flap; System allows automatic preset time in HMI for tablets start up, sampling, and shutdown rejection (not available for NIK CLASSIC or MINITAB)

    Table De-Duster & Dust Collector - based on tablets moving on a slight gradient spiral mesh;  fine dust gets exhausted and collected into the dust collector.  Tablet press is also connected to dust collector to exhaust all extra powder

    Powder Loading System - Auto Powder Loading is available if the total distance does not exceed 5 meters from the tablet press and 4 meters in height;  may be equipped with venturi system or a blower;  Auto hopper eve sensor would automatically sense low level and start the vacuum loading system.  IBC loading system may also be used

    Metal Detection Unit - Very High Metal Detection Sensitivity; PLC Digital Control and Signal Processing; Dual Channel Phase Sensitive Detection

    Dies & Punches are available in any shape and size;  some options include:

  • Lower punch lubrication for effervescent tablets
  • Lower and Upper line alignment guide for caplet shape
  • Core Rod Arrangement for Tablets w/hole
  • Upper Punch Cup Seals

    APPS - Automatic Process Parameters Sensing available for single rotary machines.  APPS allows a completely controlled process, on real time forces meter, streamline compatibility profiles, dissolution and disinteration cross-relation, raw materials evaluation, quality control and machine trouble shooting.

  • SCADA System w/15" touch screen industrial PC.  Intelligent recipe management system up to the 1,000 product/batch complies w/ 21CFR Part 11
  • Force Sensing of data including:
    • Pre-compression force
    • Main compression force
    • Ejection force
    • Real time force meters
    • Single punch statistic
    • Dwell time compression time

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Blenders

    Nicomac can supply the best blender for any type of product and any type of process.  All Nicomac blenders can be easily integrated into the process line.  Dry blending of free uniform flowing powders/granules to achieve homogeneity with the shortest process time and easy cleaning.  All systems are safe, have variable speed for precise control, and uniform, gentle mixing.  IBC Blender is the most efficient and best method of handling,  blending, and transferring any less than 3000L batch powder product.  The products are blended by continuously rotating the bin.  The cage blender has a powered clamping cage which assures the operator safety.  Different inclinations can be set for asymmetric flow of powder or granules in the bin during tumbling.

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Fluid Bed Dryer

    Nicomac's FBD combines a unique design with unmatched granulation performance and versatility for today's ever-evolving processing field.  Their system has achieved worldwide success in the Pharmaceutical industry.  Significant features that set Nicomac's FBD apart from the competition include:

  • Versatile range of sizes for processing 3kg thru 600kg
  • PLC control of inlet and outlet fans achieve very precise and flexible control
  • Specially designed baffles in the air chamber avoid air turbulences & reduces drying time
  • Optional Integrated CIP-WIP cycle with universal skid
  • High containment for the safety of the operator during processing of potent products.
  • Download PDF - Fluid Bed Dryer Brochure

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High Shear Mixer

  • NICOMIXER Made by Nicomac
  • For Dry mixing, wet mixing, and granulation, hi performance mixing thru the carefully designed features such as:
    • No mechanical friction to the product
    • Full size mixing
    • No dead point
    • High free flowing dosing properties
    • High uniformity of granule size
  • Range of sizes for processing 5kg thru 600kg
  • PLC control and touch screen HMI with integrated password level security
  • Integrated fast and effective CIP/WIP process
  • In-house product testing available
  • Download PDF - High Shear Mixer Brochure

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Pneumatic Conveying System

    Pneumatic conveying systems provides for the vacuum transport of powders, granules and other free flowing solids in a gentle, safe, closed system. Characteristics of the system include:

  • Sequential time based air blasted filter cleaning system

  • Washable filter, and provisions for reduced cleaning changeover time

  • Silencer at suction and discharge port for reduced noise levels

  • The vacuum source is equipped with filter to prevent contamination from external particles

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Complete Granulation Line

    NICOMAC can provide you a modern, high technology, fully integrated, complete granulation line.  Product flow can be accomplished thru manual or gravity systems.  Pneumatic conveying system as well as mobile and stationary lifting and discharging systems can be used.  Solid dosage form lay-out may have different philosophy and/or configuration depending on how the link between the main process steps and product handling operates.  Refer to the brochure for more complete and detailed information, including Horizontal Layout on One Level and Vertical Layout on different levels, but here's a brief list of equipment & processes offered:

  • Dispensing Room
  • Sieving - Milling & Calibration
  • High Speed Mixer/High Shear Mixer/Rapid Mixer
  • Pneumatic Conveying System
  • Fluid Bed Dryer
  • Lifting/Discharging/Transport System
  • Weighing System
  • Tablet Press
  • Blender - IBC Tumbler/Double Cone/V-Type/Octagonal Type/Drum
  • Perforated Drum Coater
  • FA-CIM Flexible Automation and Computer Integrated Management
  • WIP-CIP System
  • Download PDF - Complete Granulation Line Brochure with included Line Layouts

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Complete Modular Clean Rooms

High quality materials and finishing, customized projects, flexibility, timely and professional installation with skilled personnel, modern design for complete clean room.  Special attention paid to fine details, completely flush surfaces, equipment integration coordination.

  • Movable walls with patented system for easy disassembling: high mechanical strength, steam & chemical resistant, high dimensional stability, high impact resistance, anti-scratch surface, maintenance free, easy and fast installation, modifications on site
  • Modular false ceiling, standard and walk-on type
  • Optional uPVC, and Epoxy coated walls
  • Swing out and sliding doors with rounded profiles
  • Flush Glazed panel with anti-condensation profiles
  • Electric sockets and fittings recessed and flush with the wall
  • Quick Delivery is available
  • Download PDF - Nicomac Clean Rooms
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Accessories for Clean Rooms

  • Made by Nicomac
  • DECONJET atomizer for cleanroom biodecontamination;  designed for regular and periodic cleanroom fogging
  • STERICLEAN - system for cleaning and biodecontamination of surfaces
  • SPRAYCLEAN automatic atomizer for gloved hands disinfecting;  no drainage system required
  • SS sinks & basins, Benches, Personnel Lockers, Bumpers/Wall Guards, Sliding Doors, Pass Thru Units, Drains & Traps
  • Dispensing Rooms
  • Download PDF - Clean Room Accessories
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Pass Box and Phone

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WIP/CIP Modular Skid

    A Universal Modular Skid is available from Nicomac, designed to clean efficiently and rapidly all machinery and components in the granulation line.  Stainless Steel framework on wheels including: connection clamps, piping, sanitary valves, filters, high sanitary pressure pump, heated tank for purified water, detergent and emptying pump.  Includes a drying unit.  Two motorized washing arms with 4-way direction orbital washing nozzles are fitted inside all granulation machinery to guarantee perfect cleaning.  PLC control of the system with up to 20 different washing recipes.

Characteristics:

  • Movable unit w/patented OCTOPUS flange - movable flange to be fitted with an easy and fast operation, by means of suction cups, to different coating pan and equipment - tightening resistant to 90 bars

  • Purified water tank

  • Automatic motion of HION nozzle arm (High Impact Orbital Nozzle)

  • Booster and high pressure pump (18-80 bars)

  • Detergent unit

  • Emptying pump

  • Sanitary flexible hose, pipe, filters, and valves

  • PLC Control System

  • Download PDF - WIP/CIP Skid Brochure

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Last modified: 12/20/09