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AWS Bio-Pharma
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Aseptic Processing
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Steriline
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PennTech
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& Carts
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Non-Aseptic
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AWS represents the highest
quality, new biotech and pharmaceutical manufacturing equipment
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About Nicomac
NICOMAC Company Mission: Our Goal is High
Quality and the Highest Technology for your success
NICOMAC was founded in 1977. Our success all over the world is due to our
Company Philosophy focused on a constant innovation and care of customer.
We aim to become the partner of choice by providing solutions based on advanced
and unique technologies that give to our customer a competitive advantage.
All NICOMAC projects are based on detailed drawings, controlled and validated
design, care of details, respect of the production and installation time
schedule, fast and reactive communication. A young, dynamic, flexible
organization, who pay high attention of customer's requirements, skilled and
experienced personnel , proactive and communicative management will take you to
success of your valuable projects. Nicomac has 4 lines of products:
- NCS Nicomatic Coating System combines a unique design with
unmatched coating equipment performance, high technology and versatility for
today's ever-evolving pharmaceutical and confectionery processing field.
- HI HIPHARMA Clean Room line is Nicomac's answer to the high
quality standard required by the Pharmaceutical industry. Our clean rooms
system combine quality and innovation at a competitive price. Standard and
custom walls, doors, false ceilings, and accessories: the most advanced
systems in the marketplace.
- NGL Granulation line - A complete line of granulation machinery
for a turn-key supply: Dispensing Room, Granulation , Handling, Mixing.
-
Download PDF - Nicomac General Presentation and Overview
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Table Top, Lab
Scale Tablet Press
Nicomac's MINITAB Series of Single
Rotary Tablet Presses is an idea press for R&D operations, designed with
Flexibility, Reliability, and Ease of Scale-Up in mind. With a max output
of 27,000 tablets/hr, and available tooling for D, B, or BB tablets, the MINITAB
Tablet Press is perfect for your
R&D and lab
operations
- MINITAB Tabletop Rotary Tablet Press made by NICOMAC
- Can be integrated with APPS
- D, B, BB Tooling for up to 27,000 tablets/hr
- cGMP and CE compliant
- Max compressive force of 10tons
- Machine dimensions - 0.46m x 0.62m x 1.1m (+table)
-
Download PDF - MINITAB Brochure
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Single Rotary Tablet Press
Nicomac's NIK SMART Series of Single Rotary Tablet Presses are one of the most
modern, compact, and reliable rotary presses on the market. With a max
output of 118,000 tablets/hr, and available tooling for D, B, or BB tablets, the
SMART Tablet Press is perfect for your low to mid speed applications
- Can be integrated with APPS
- cGMP and CE compliant
- Max compressive force of 10tons
- Machine dimensions - 1m x 1m x 1.8m
- Precompression for difficult/fluffy/fine granules
- HOS: Hydraulic Overload System to protect
turret/dies/punches and avoid possible damage
- Interlocking on upper and lower guards and audio
visual alarm available for maximum safety
-
Download PDF - All Rotary Tablet Presses
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Double Rotary Tablet
Presses
Nicomac's NIK CLASSIC Series of Double
Rotary Tablet Presses are made for production efficiency and the highest
reliability on the market. It be configured for double output or
double layer execution. With a max output of 270,000 tablets/hr, and
available tooling for D, B, or BB tablets, the CLASSIC Tablet Press is perfect
for your mid to mid/hi speed applications
- Optimized for stability
and maximum operating reliability
- cGMP and CE compliant
- PLC Control and HMI
w/alphanumeric display
- Compression Spring
Counterbalance System
- HOS, Pre Compression
and 3-way Discharge is not available on this model
- Machine dimensions -
1.1m x 1.1m x 1.8m
- Interchangeable Gravity Feeder or Force Feeder
- Interlocking on upper and lower guards and audio
visual alarm available for maximum safety
-
Download PDF - All Rotary Tablet Presses
Nicomac's NIK SPECIAL Series of Double Rotary Tablet Presses have an
ultra-modern design using unique sliding pressure rolls. With a max output
of 583,000 tablets/hr, and available tooling for D, B, BB or BBsp tablets, the
NIK SPECIAL Tablet Press is perfect for your mid to hi speed applications
- Unique sliding pressure
rolls
- Optimized Stability and dust tight seals
- No cross contamination
- D, B, BB and BBsp
Tooling for up to 583,000 tablets/hr
- cGMP and CE compliant
- PLC Control and 10.4"
Touch screen HMI
- Machine dimensions -
1.25m x 1.45m x 1.95m
-
Download PDF - All Rotary Tablet Presses
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Triple Rotary Tablet Press
Nicomac's NIK Triple Series of Triple Rotary Tablet Presses are made for
production efficiency and the highest reliability on the market. It
be configured for triple output or triple layer execution. With a max
output of 658,000 tablets/hr, and available tooling for D, or B tablets, the
TRIPLE Tablet Press is perfect for your mid to hi speed applications
- Unique sliding pressure
rolls
- Compression zone is
totally isolated
- D or B Tooling for up
to 658,000 tablets/hr
- cGMP and CE compliant
- PLC Control and HMI
w/alphanumeric display
- Machine dimensions -
1.25m x 1.45m x 1.95m
-
Download PDF - All Rotary Tablet Presses
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Conventional
Coating Pans
The Nicomac Coating System (NCS) combines a unique design with unmatched
coating performance and versatility for today's ever-evolving processing field.
Our system has achieved worldwide success in both the Pharmaceutical and
Confectionery industries. The following are just a few of the significant
features that set us apart from the competition:
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Versatility: capable of aqueous & organic film or sugar coating of tablets,
pellets
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Capacity:
ranges from lab scale (10L) up to manufacturing production (2,300L)
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Special
drums and Unique drying system allows for same high efficiency when working
with 15-20% of the drum capacity
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Shark Fin
Baffles: Patented "3D Shark Fin Baffles" combine higher mixing efficiency
with gentler product handling to result in improved coating uniformity,
thanks to the uniform distribution of spraying solution, thus reducing
overall process time
-
Download PDF here for complete
list of Nicomac's Coating System Advantages!
-
Download PDF of Nicomac Coating Line Card

Tablet Processing
Accessories
3-Way Discharge - efficient 3 way discharge with pneumatic flap; System allows
automatic preset time in HMI for tablets start up, sampling, and shutdown
rejection (not available for NIK CLASSIC or MINITAB)
Table De-Duster & Dust Collector - based on tablets moving on a slight gradient
spiral mesh; fine dust gets exhausted and collected into the dust
collector. Tablet press is also connected to dust collector to exhaust all
extra powder
Powder Loading System - Auto Powder Loading is available if the total distance
does not exceed 5 meters from the tablet press and 4 meters in height; may
be equipped with venturi system or a blower; Auto hopper eve sensor would
automatically sense low level and start the vacuum loading system. IBC
loading system may also be used
Metal Detection Unit - Very High Metal Detection Sensitivity; PLC Digital
Control and Signal Processing; Dual Channel Phase Sensitive Detection
Dies & Punches are available in any shape and size; some options include:
- Lower punch lubrication for effervescent tablets
- Lower and Upper line alignment guide for caplet shape
- Core Rod Arrangement for Tablets w/hole
- Upper Punch Cup Seals
APPS - Automatic Process Parameters Sensing
available for single rotary machines. APPS allows a completely controlled
process, on real time forces meter, streamline compatibility profiles,
dissolution and disinteration cross-relation, raw materials evaluation, quality
control and machine trouble shooting.
- SCADA System w/15" touch screen industrial
PC. Intelligent recipe management system up to the 1,000 product/batch
complies w/ 21CFR Part 11
- Force Sensing of data including:
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Pre-compression force
- Main compression force
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Ejection force
- Real time force meters
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Single punch statistic
- Dwell time compression time
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Blenders
Nicomac can supply the best blender for any type of product and any type of
process. All Nicomac blenders can be easily integrated into the process
line. Dry blending of free uniform flowing powders/granules to achieve
homogeneity with the shortest process time and easy cleaning. All systems
are safe, have variable speed for precise control, and uniform, gentle mixing.
IBC Blender is the most efficient and best method of handling, blending,
and transferring any less than 3000L batch powder product. The products
are blended by continuously rotating the bin. The cage blender has a
powered clamping cage which assures the operator safety. Different
inclinations can be set for asymmetric flow of powder or granules in the bin
during tumbling.
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Fluid Bed Dryer
Nicomac's FBD combines a unique design with unmatched granulation performance
and versatility for today's ever-evolving processing field. Their system
has achieved worldwide success in the Pharmaceutical industry. Significant
features that set Nicomac's FBD apart from the competition include:
- Versatile range of sizes for processing 3kg
thru 600kg
- PLC control of inlet and outlet fans
achieve very precise and flexible control
- Specially designed baffles in the air
chamber avoid air turbulences & reduces drying time
- Optional Integrated CIP-WIP cycle with
universal skid
- High containment for the safety of the
operator during processing of potent products.
-
Download PDF - Fluid Bed Dryer Brochure
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High Shear Mixer
- NICOMIXER Made by
Nicomac
- For Dry mixing,
wet mixing, and granulation, hi performance mixing thru
the carefully designed features such as:
- No mechanical
friction to the product
- Full size mixing
- No dead point
- High free flowing
dosing properties
- High uniformity
of granule size
- Range of sizes
for processing 5kg thru 600kg
- PLC control and
touch screen HMI with integrated password level security
- Integrated fast
and effective CIP/WIP process
- In-house product
testing available
-
Download PDF - High Shear Mixer Brochure
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Pneumatic Conveying
System
Pneumatic conveying systems provides for the vacuum transport of powders,
granules and other free flowing solids in a gentle, safe, closed system.
Characteristics of the system include:
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Sequential time based air blasted filter
cleaning system
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Washable filter, and provisions for reduced
cleaning changeover time
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Silencer at suction and discharge port for
reduced noise levels
-
The vacuum source is equipped with filter to
prevent contamination from external particles
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Complete
Granulation Line
NICOMAC can provide you a modern, high technology, fully integrated, complete
granulation line. Product flow can be accomplished thru manual or gravity
systems. Pneumatic conveying system as well as mobile and stationary
lifting and discharging systems can be used. Solid dosage form lay-out may
have different philosophy and/or configuration depending on how the link between
the main process steps and product handling operates. Refer to the
brochure for more complete and detailed information, including Horizontal Layout
on One Level and Vertical Layout on different levels, but here's a brief list of
equipment & processes offered:
-
Dispensing Room
- Sieving - Milling & Calibration
- High Speed Mixer/High Shear Mixer/Rapid
Mixer
- Pneumatic Conveying System
- Fluid Bed Dryer
-
Lifting/Discharging/Transport System
- Weighing System
- Tablet Press
- Blender - IBC Tumbler/Double
Cone/V-Type/Octagonal Type/Drum
-
Perforated Drum Coater
- FA-CIM Flexible Automation and Computer
Integrated Management
- WIP-CIP System
-
Download PDF - Complete Granulation Line Brochure with included Line Layouts
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Complete Modular
Clean Rooms
High quality
materials and finishing, customized projects, flexibility, timely and
professional installation with skilled personnel, modern design for complete
clean room. Special attention paid to fine details, completely flush
surfaces, equipment integration coordination.
- Movable walls with
patented system for easy disassembling: high mechanical
strength, steam & chemical resistant, high dimensional
stability, high impact resistance, anti-scratch surface,
maintenance free, easy and fast installation,
modifications on site
- Modular false ceiling,
standard and walk-on type
- Optional uPVC, and
Epoxy coated walls
- Swing out and sliding
doors with rounded profiles
- Flush Glazed panel with
anti-condensation profiles
- Electric sockets and
fittings recessed and flush with the wall
- Quick Delivery is
available
-
Download PDF - Nicomac Clean Rooms
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Accessories for
Clean Rooms
- Made by Nicomac
- DECONJET atomizer
for cleanroom biodecontamination; designed for
regular and periodic cleanroom fogging
- STERICLEAN -
system for cleaning and biodecontamination of surfaces
- SPRAYCLEAN
automatic atomizer for gloved hands disinfecting;
no drainage system required
- SS sinks &
basins, Benches, Personnel Lockers, Bumpers/Wall Guards,
Sliding Doors, Pass Thru Units, Drains & Traps
- Dispensing Rooms
-
Download PDF - Clean Room Accessories
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WIP/CIP Modular
Skid
A Universal Modular Skid is available from Nicomac, designed to clean
efficiently and rapidly all machinery and components in the granulation line.
Stainless Steel framework on wheels including: connection clamps, piping,
sanitary valves, filters, high sanitary pressure pump, heated tank for purified
water, detergent and emptying pump. Includes a drying unit. Two
motorized washing arms with 4-way direction orbital washing nozzles are fitted
inside all granulation machinery to guarantee perfect cleaning. PLC
control of the system with up to 20 different washing recipes.
Characteristics:
-
Movable unit w/patented OCTOPUS flange -
movable flange to be fitted with an easy and fast operation, by means of
suction cups, to different coating pan and equipment - tightening resistant
to 90 bars
-
Purified water tank
-
Automatic motion of HION nozzle arm (High
Impact Orbital Nozzle)
-
Booster and high pressure pump (18-80 bars)
-
Detergent unit
-
Emptying pump
-
Sanitary flexible hose, pipe, filters, and
valves
-
PLC Control System
-
Download PDF - WIP/CIP Skid Brochure
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